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Drug Fluconazole Instruction Description


2017-12-28 00:00:00

Name: Fluconazole Fluconazole

Pharmacological action:
Has a strong antifungal activity; specifically inhibits inhibits the synthesis of fungal sterols.
Rapidly absorbed when taken orally. Long stored in plasma. Write mainly kidneys up to 80%.


Indications:
Used in a variety of fungal infections: cryptococcosis with disease of the central nervous system causes a parasitic yeast microorganisms, including cryptococcal meningitis inflammation of the brain caused by a parasitic yeast-like organisms; with systemic candidiasis, a fungal disease, candidiasis of the mucous membranes, vaginal candidiasis; for the prevention of fungal infections in patients with malignancies in the treatment of cytostatic agents that suppress cell division or radiotherapy in organ and in other cases where the depressed immune system and there is a risk of fungal infection.


Dosing:
Administered orally and intravenously. Daily dose of both methods of using same. Because of the long half-life time, during which the body is derived from `/2 of the administered dose of the drug is sufficient to take the drug once a day 1. Usual therapeutic doses ranging from 200 mg to 400 mg per day, with mucosal candidiasis -50-100 mg per day; vaginal candidiasis -150 mg. The duration of treatment depends on the nature of the disease and efficacy of 7-14 to 30 days.


Side effects:
Usually well tolerated. Possible diarrhea diarrhea, flatulence gas accumulation in the intestine, skin rashes.


Contraindications:
The drug should not be administered during pregnancy and breastfeeding, as well as children under 16 years.
Fluconazole increases the effects of anticoagulants, oral hypoglycemic agents, hydrochlorothiazide, difenina. When combined with rifampin half-life of fluconazole is shortened, and therefore need some increase in the dose.


Product:
50 capsules; 100; 150 and 200 mg. Syrup containing 5 mg in 1 ml 0.5%. 0.2% solution in isotonic sodium chloride solution for intravenous administration.


Storage conditions:
List B. In the dark spot.


Synonyms:
Diflucan, Medoflyukon, Fluzon.


Attention!
Before using the drug Fluconazole , you should consult your doctor. This operating instruction is given a free transfer and is intended solely for information. For more information, please contact the manufacturer annotations.





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