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Pimafucin Instructions Description of the drug


2017-12-28 00:00:00

Name: Pimafucin Pimafucin

Pharmacological action:
Pimafutsin -antifungal agent. Active ingredient of the drug is natamycin -polyene macrolide antibiotic series. It has a wide spectrum of action. Shows the fungicidal activity, as sterols blocks of cell membranes of fungi, which leads to death of the microorganism. Sensitive to the fungi of the genus Candida spp. Slightly lower sensitivity manifests dermatophytes. To date, in clinical practice no cases of resistance to natamycin.

Natamycin is practically not absorbed in the gut, is not absorbed from the mucous membranes and skin. Due to the enteric coating tablets Pimafutsin effect observed in the intestines.


Indications:
Fungal etiology of infection caused by microorganisms sensitive to natamycin:
• Vulvovaginal candidiasis;
• Fungal diseases of the gastrointestinal tract caused by the failure of immunity, cachexia receiving cytostatics, antibiotics, corticosteroids including atrophic and acute pseudomembranous candidiasis, intestinal candidiasis;
• Comprehensive treatment in the case of systemic fungal disease;
• Fungal infections of the skin and skin appendages nails.


Dosing:
class="prp_under"> Pimafucin Tablets
Intestinal candidiasis -1 tablet 4 p/day for adults, course of treatment -7 days. Children: 1 tablet 2 p/day.
Candidiasis nail in addition to applying the cream Pimafucin -1 tablet 4 p/day, course of treatment is 2-3 months.
Vulvovaginal candidiasis in addition to intravaginal suppository Pimafucin for sanitation hearth kandidomikoznoy infection in the gut -1 tablet 4 p/day treatment course of 10-20 days.
Common skin candidiasis in addition to local usage Pimafucin cream -1 tablet 4 p/day, course of treatment -7 days.
In onihomikozah in addition to local usage Pimafucin cream -1 tablet 4 p/day, course of treatment -2-3 months.

class="prp_under"> Pimafucin Suppositories
When vulvovaginal candidiasis -1 suppository deep into the vagina one time a day at bedtime. You must enter in the supine position. The duration of therapy is determined individually. The average course of treatment -3-6 days. Once symptoms are urged to continue intravaginal administration for 2-3 days.

class="prp_under"> Pimafucin Cream
When ringworm, candidiasis including nail or skin -apply the cream to the affected area of the skin or nails from 1 to 4 p/day. The course of treatment -2-3 weeks.
For the treatment of candidiasis lesions character in a sexual partner -applied to the anogenital area and fungal diseases of the intestine, in addition to lozenges Pimafucin.


Side effects:
When receiving natamycin tablets possible diarrhea and nausea at the beginning of therapy, which disappear spontaneously upon further treatment.
When using topical natamycin cream, suppositories may be a burning sensation and poorly marked irritation of the surrounding tissues.


Contraindications:
Hypersensitivity reactions to components pimafutsin.


Pregnancy:
Pimafutsin not contraindicated in pregnant women, nursing and newborn.


Interaction with other medicinal products:
Not reveal any clinically significant interaction.


Overdose:
Due to the low absorption of overdose is unlikely.


Product:
Tablets coated with enteric coating. 100 mg of natamycin per one tablet. In contour pack of 20 tablets.
Vaginal suppositories. 100 mg of natamycin per 1 suppository. In blister 3 suppository.
Cream 2% in tubes of 30 g in 1 g of cream -20 mg natamycin.


Storage conditions:
Temperature of 15-25 ° C.


Ingredients:
class="prp_under"> Pimafucin Tablets
Active ingredient: natamycin.
Additional substances: polyvinyl pyrrolidone, potato starch, magnesium stearate, gelatine, lactose, acacia, methyl parahydroxybenzoate, talc, calcium carbonate, kaolin, triacetin, titanium dioxide, atsetatftalattsellyuloza, white beeswax, sucrose.

class="prp_under"> Vaginal suppositories Pimafucin
Active ingredient: natamycin.
Additional material: solid fat, cetyl alcohol, polysorbate 80, sorbitan trioleate, sodium bicarbonate, adipic acid.

class="prp_under"> Pimafucin Cream
Active ingredient: natamycin.
Additional ingredients: decyl oleate, tsetostearinovy alcohol, cetyl ester wax, sodium lauryl sulfate, Valium, propylene glycol, Propyl, purified water.


Extras:
Suppositories for intravaginal rapidly melt at body temperature, forming a bulk foaming mass -it improves the even distribution along the walls of the vagina of the active drug substance. In the case of chronic vulvovaginal candidiasis therapy combined with taking pills or cream Pimafucin. The period of menstruation temporarily stop administering suppositories. The composition of suppositories include cetyl alcohol, which can provoke an allergic reaction. During treatment suppositories Pimafucin exclude sex life is not necessarily.


Attention!
Before using the medication Pimafucin , you should consult your doctor. This operating instruction is given a free transfer and is intended solely for information. For more information, please contact the manufacturer annotations.





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